Biological process
negative regulation of insulin receptor signaling pathway
Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
Definition from the Gene Ontology (GO:0046627), read 2026-09-23. CC BY 4.0.
GO:0046627Gene Ontology
What the reference databases state
Statements
35 statements
35 statements · 1 reference database · Subject: negative regulation of insulin receptor signaling pathway · Sources: gene ontology
- AHSG regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P02765|GO:0046627Inferred only
- BLVRB regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P30043|GO:0046627Inferred only
- CUL7 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q14999|GO:0046627Inferred only
- ENPP1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P22413|GO:0046627Inferred only
- FBXW8 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q8N3Y1|GO:0046627Inferred only
- GRB10 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q13322|GO:0046627Inferred only
- GRB14 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q14449|GO:0046627Inferred only
- GSK3A regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P49840|GO:0046627Inferred only
- IL1B regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P01584|GO:0046627Inferred only
- INPP5K regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q9BT40|GO:0046627Inferred only
- IRS1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P35568|GO:0046627Inferred only
- KANK1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q14678|GO:0046627Inferred only
Show the remaining 23
- MAPKAP1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q9BPZ7|GO:0046627Inferred only
- MSTN regulates negative regulation of insulin receptor signaling pathwayProteingene ontology O14793|GO:0046627Inferred only
- MTOR regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P42345|GO:0046627Inferred only
- NCK1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P16333|GO:0046627Inferred only
- PID1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q7Z2X4|GO:0046627Inferred only
- PIP4K2A regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P48426|GO:0046627Inferred only
- PIP4K2B regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P78356|GO:0046627Inferred only
- PIP4K2C regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q8TBX8|GO:0046627Inferred only
- PRKAA1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q13131|GO:0046627Inferred only
- PRKCB regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P05771|GO:0046627Inferred only
- PRKCD regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q05655|GO:0046627Inferred only
- PRKCQ regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q04759|GO:0046627Inferred only
- PRKCZ regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q05513|GO:0046627Inferred only
- PTPN1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P18031|GO:0046627Inferred only
- PTPN2 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P17706|GO:0046627Inferred only
- PTPRE regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P23469|GO:0046627Inferred only
- RBX1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P62877|GO:0046627Inferred only
- RPS6KB1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology P23443|GO:0046627Inferred only
- SLC27A4 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q6P1M0|GO:0046627Inferred only
- SOCS1 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology O15524|GO:0046627Inferred only
- TNS2 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q63HR2|GO:0046627Inferred only
- TRIB3 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q96RU7|GO:0046627Inferred only
- UCN2 regulates negative regulation of insulin receptor signaling pathwayProteingene ontology Q96RP3|GO:0046627Inferred only