Biological process
negative regulation of gene expression, epigenetic
An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation.
Definition from the Gene Ontology (GO:0045814), read 2026-09-23. CC BY 4.0.
GO:0045814Gene Ontology
What the reference databases state
Statements
38 statements
38 statements · 1 reference database · Subject: negative regulation of gene expression, epigenetic · Sources: gene ontology
- BMI1 regulates negative regulation of gene expression, epigeneticProteingene ontology P35226|GO:0045814Inferred only
- CHEK1 regulates negative regulation of gene expression, epigeneticProteingene ontology O14757|GO:0045814Inferred only
- CREBZF regulates negative regulation of gene expression, epigeneticProteingene ontology Q9NS37|GO:0045814Inferred only
- DNMT3L regulates negative regulation of gene expression, epigeneticProteingene ontology Q9UJW3|GO:0045814Inferred only
- EPC1 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9H2F5|GO:0045814Inferred only
- EZH2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q15910|GO:0045814Inferred only
- HDAC1 regulates negative regulation of gene expression, epigeneticProteingene ontology Q13547|GO:0045814Inferred only
- HDAC4 regulates negative regulation of gene expression, epigeneticProteingene ontology P56524|GO:0045814Inferred only
- HDAC5 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9UQL6|GO:0045814Inferred only
- HDAC6 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9UBN7|GO:0045814Inferred only
- HDAC9 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9UKV0|GO:0045814Inferred only
- HEMK2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9Y5N5|GO:0045814Inferred only
Show the remaining 26
- IFI16 regulates negative regulation of gene expression, epigeneticProteingene ontology Q16666|GO:0045814Inferred only
- ING2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9H160|GO:0045814Inferred only
- LHX2 regulates negative regulation of gene expression, epigeneticProteingene ontology P50458|GO:0045814Inferred only
- MACROH2A1 regulates negative regulation of gene expression, epigeneticProteingene ontology O75367|GO:0045814Inferred only
- MACROH2A2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9P0M6|GO:0045814Inferred only
- METTL4 regulates negative regulation of gene expression, epigeneticProteingene ontology Q8N3J2|GO:0045814Inferred only
- MPHOSPH8 regulates negative regulation of gene expression, epigeneticProteingene ontology Q99549|GO:0045814Inferred only
- MTA1 regulates negative regulation of gene expression, epigeneticProteingene ontology Q13330|GO:0045814Inferred only
- MTF2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9Y483|GO:0045814Inferred only
- PCID2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q5JVF3|GO:0045814Inferred only
- PHF1 regulates negative regulation of gene expression, epigeneticProteingene ontology O43189|GO:0045814Inferred only
- PHF19 regulates negative regulation of gene expression, epigeneticProteingene ontology Q5T6S3|GO:0045814Inferred only
- PPHLN1 regulates negative regulation of gene expression, epigeneticProteingene ontology Q8NEY8|GO:0045814Inferred only
- PPM1D regulates negative regulation of gene expression, epigeneticProteingene ontology O15297|GO:0045814Inferred only
- RIF1 regulates negative regulation of gene expression, epigeneticProteingene ontology Q5UIP0|GO:0045814Inferred only
- SAMD7 regulates negative regulation of gene expression, epigeneticProteingene ontology Q7Z3H4|GO:0045814Inferred only
- SDR16C5 regulates negative regulation of gene expression, epigeneticProteingene ontology Q8N3Y7|GO:0045814Inferred only
- SIRT6 regulates negative regulation of gene expression, epigeneticProteingene ontology Q8N6T7|GO:0045814Inferred only
- SIRT7 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9NRC8|GO:0045814Inferred only
- SMYD5 regulates negative regulation of gene expression, epigeneticProteingene ontology Q6GMV2|GO:0045814Inferred only
- SUV39H2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q9H5I1|GO:0045814Inferred only
- TASOR regulates negative regulation of gene expression, epigeneticProteingene ontology Q9UK61|GO:0045814Inferred only
- TASOR2 regulates negative regulation of gene expression, epigeneticProteingene ontology Q5VWN6|GO:0045814Inferred only
- TFAP2C regulates negative regulation of gene expression, epigeneticProteingene ontology Q92754|GO:0045814Inferred only
- TRIM27 regulates negative regulation of gene expression, epigeneticProteingene ontology P14373|GO:0045814Inferred only
- TRIM37 regulates negative regulation of gene expression, epigeneticProteingene ontology O94972|GO:0045814Inferred only