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Proteins/UNIPROT:Q5VWN6
Core component of the HUSH2 complex, a multiprotein complex that mediates epigenetic repression of interferon-stimulated genes. TASOR2 is recruited to interferon-stimulated genes by IRF2, leading to transcriptional silencing by the HUSH2 complex via a H3K9me3-independent mechanism. Within the HUSH2 complex, TASOR2 acts as the central scaffold, which recruits MPHOSPH8 and PPHLN1..
Function from UniProtKB (Q5VWN6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
15 statements
15 statements · 2 reference databases · Subject: TASOR2 · Sources: gene ontology, Hetionet
4 names
Resolves to: TASOR2