Proteins/UNIPROT:Q9NS37

CREBZF

ProteinUNIPROT:Q9NS37

Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells..

Function from UniProtKB (Q9NS37), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

15 statements

15 statements · 2 reference databases · Subject: CREBZF · Sources: gene ontology, Hetionet

Order

GLTP covaries with CREBZFProteinHetionet hetionet:covaries:51228-58487Inferred only
ZNF34 covaries with CREBZFProteinHetionet hetionet:covaries:58487-80778Inferred only
ATF4 interacts with CREBZFProteinHetionet hetionet:interacts:468-58487Inferred only
CREBZF interacts with CREB3L3ProteinHetionet hetionet:interacts:58487-84699Inferred only
HCFC1 interacts with CREBZFProteinHetionet hetionet:interacts:3054-58487Inferred only
PPARGC1A interacts with CREBZFProteinHetionet hetionet:interacts:10891-58487Inferred only
SIRT1 interacts with CREBZFProteinHetionet hetionet:interacts:23411-58487Inferred only
UBC interacts with CREBZFProteinHetionet hetionet:interacts:58487-7316Inferred only
ZNF512B interacts with CREBZFProteinHetionet hetionet:interacts:57473-58487Inferred only
CREBZF regulates negative regulation of DNA-templated transcriptionBiological processgene ontology Q9NS37|GO:0045892Inferred only
CREBZF regulates negative regulation of gene expression, epigeneticBiological processgene ontology Q9NS37|GO:0045814Inferred only
CREBZF regulates positive regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NS37|GO:0045944Inferred only

Show the remaining 3

CREBZF regulates regulation of transcription by RNA polymerase IIBiological processgene ontology Q9NS37|GO:0006357Inferred only
POLR2K increases the expression of CREBZFProteinHetionet hetionet:regulates:5440-58487Inferred only
ZNF365 increases the expression of CREBZFProteinHetionet hetionet:regulates:22891-58487Inferred only

Other names

3 names

Resolves to: CREBZF

Also called: HCF-binding transcription factor ZhangfeiHost cell factor-binding transcription factor ZhangfeiZF

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