Pathway
Synthesis of 5-eicosatetraenoic acids
5-hydroperoxy-eicosatetraenoic acid (5-HpETE), 5-hydroxyeicosatetraenoic acid (5S-HETE) and 5-oxo-eicosatetraenoic acid (5-oxoETE) are formed after the initial step of Arachidonate oxidation by arachidonate 5-lipoxygenase (ALOX5).
REACT:R-HSA-2142688Reactome
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: Synthesis of 5-eicosatetraenoic acids · Sources: Reactome
- ALOX5 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- ALOX5AP participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- GPX1 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- GPX2 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- GPX4 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- LTC4S participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- PON1 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- PON2 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only
- PON3 participates in Synthesis of 5-eicosatetraenoic acidsProteinReactome R-HSA-2142688Inferred only