Delayed-onset muscle soreness

Method

Perceived soreness on a named validated scale — visual analogue scale (VAS) or Likert — at a stated interval after a damaging bout. Instrument and interval recorded on the edge.

The method is part of the endpoint identity. Studies measuring the same quantity by a different method are held as separate endpoints.

Notes

Admitted on the same grounds as subjective-fatigue: it is self-reported but measured with an instrument at a defined time point. The interval is not optional metadata — soreness peaks 24 to 72 hours post-exercise, so an edge without it does not identify what was measured.

Findings

1 finding from 1 compound, strongest first.

• curcumin — decreases

  BLikelyGrade B, Likely. Human evidence, limited replication or design limits.Finding

  “The combined effect size for curcumin supplementation in mitigating muscle soreness registers at mean difference (MD) = -0.61, signifying a substantial reduction in pain, particularly in cases of lower back pain.”

  Study

  meta-analysis

  Population

  trained and untrained adults undergoing muscle-damaging exercise

  Effect -0.61 mean difference

  Meta-analysis of the effect of curcumin supplementation on skeletal muscle damage status.2024PMID:39008500