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Reference

Evidence

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2-hydroxy-3-oxopropanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

4 compounds within 3 steps: 1 in 1, 1 in 2, 2 in 3

Does it reach a compound?

One step

3-hydroxypyruvateReach from here →
1. 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate
Catalysed by HYI

Two steps

(R)-glycerateReach from here →
1. 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate
2. (R)-glycerate + NAD(+) = 3-hydroxypyruvate + NADH + H(+)
Catalysed by HYI, GRHPROne of 2 routes

Three steps

(2R)-3-phosphoglycerateReach from here →
Catalysed by HYI, GRHPR, GLYCTKcytosolOne of 3 routes
(2R)-2-phosphoglycerateReach from here →
Catalysed by HYI

cytosol