Compound

2-hydroxy-3-oxopropanoate

The conjugate base of 2-hydroxy-3-oxopropanoic acid; major species at pH 7.3.

Definition from ChEBI (CHEBI:57978), read 2026-09-23. CC BY 4.0.

CHEBI:57978ChEBI

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Structure

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A generated conformer of 2-hydroxy-3-oxopropanoate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C3H3O4
Mass: 103.053 g/mol
Charge: -1
InChIKey: QWBAFPFNGRFSFB-UHFFFAOYSA-M
SMILES: [H]C(=O)C(O)C(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What the reference databases state

Statements

10 statements

10 statements · 2 reference databases · Subject: 2-hydroxy-3-oxopropanoate · Sources: Human-GEM, Rhea

Order

2-hydroxy-3-oxopropanoate is converted to (R)-glycerateCompoundRhea RHEA:18841Inferred only
(R)-glycerate is converted to 2-hydroxy-3-oxopropanoateCompoundRhea RHEA:18845Inferred only
(R)-glycerate is converted to 2-hydroxy-3-oxopropanoateCompoundRhea RHEA:18841Inferred only
2-hydroxy-3-oxopropanoate is converted to (R)-glycerateCompoundRhea RHEA:18845Inferred only
2-hydroxy-3-oxopropanoate is converted to 3-hydroxypyruvateCompoundRhea RHEA:11952Inferred only
3-hydroxypyruvate is converted to 2-hydroxy-3-oxopropanoateCompoundRhea RHEA:11952Inferred only
3-hydroxypyruvic acid is converted to 2-hydroxy-3-oxopropanoateCompoundHuman-GEM MAR04466Inferred only
glyoxylate is converted to 2-hydroxy-3-oxopropanoateCompoundRhea RHEA:10136Inferred only
2-hydroxy-3-oxopropanoate is converted to glyoxylateCompoundRhea RHEA:10136Inferred only
2-hydroxy-3-oxopropanoate is a substrate of HYIProteinRhea RHEA:11952Inferred only

Reactions

8 reactions

3-hydroxypyruvic acid2-hydroxy-3-oxopropanoate
Catalysed by HYI
Reaction pageLeft to rightBalancedEC 5.3.1.22cytosol
Human-GEM MAR04466CC BY 4.0Reference data
2glyoxylate+hydron2-hydroxy-3-oxopropanoate+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:10136CC BY 4.0Reference data
CHEBI:580982-hydroxy-3-oxopropanoate+pyruvate
Reaction pageDirection not assertedBalanced
Rhea RHEA:10268CC BY 4.0Reference data
3-hydroxypyruvate2-hydroxy-3-oxopropanoate
Catalysed by HYI
Reaction pageDirection not assertedBalanced
Rhea RHEA:11952CC BY 4.0Reference data
CHEBI:17795+hydron2-hydroxy-3-oxopropanoate+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:13845CC BY 4.0Reference data
(R)-glycerate+NADP(3-)2-hydroxy-3-oxopropanoate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:18841CC BY 4.0Reference data
(R)-glycerate+NAD(1-)2-hydroxy-3-oxopropanoate+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:18845CC BY 4.0Reference data
CHEBI:428192-hydroxy-3-oxopropanoate+pyruvate
Reaction pageDirection not assertedBalanced
Rhea RHEA:27726CC BY 4.0Reference data

Other names

3 names

Resolves to: 2-hydroxy-3-oxopropanoate

Also called: 2-hydroxy-3-oxopropanoate anion2-hydroxy-3-oxopropanoate(1-)2-hydroxy-3-oxopropanoate(1−)