beta-D-fructose 6-phosphate

Three steps

• hexadecanedioyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Production of Hexadecanedioylcarnitine

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, CPT1A and 2 morecytosolOne of 2 routes

• pristanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. fatty-acid-CoA ligase

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2cytosolOne of 2 routes

• undecanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. medium-chain acyl-CoA ligase (undecylic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, ACSM4 and 5 morecytosolOne of 3 routes

• (5Z)-tetradecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (physeteric acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 8 routes

• (3E)-decenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, ACADM and 3 morecytosol, mitochondrial matrix

• (2R,6)-dimethylheptanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, HADHA and 2 morecytosol, mitochondrial matrix

• (7Z)-hexadecenoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 8 routes

• tricosanoyl-CoAReach from here →
  1. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)
  2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
  3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)

  Catalysed by GNPDA1, GNPDA2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 4 routes