dodecanal

Three steps

• 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. long-chain-fatty-acid-CoA ligase (lauric acid)
  3. 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 7 morecytosol

• beta-D-glucosyl-N-dodecanoylsphing-4-enineReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. N-dodecanoylsphing-4-enine + H2O = dodecanoate + sphing-4-enine
  3. beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = N-dodecanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside

  Catalysed by ALDH3A2, NAAA, ASAH1, ACER2 and 2 more

• 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. long-chain-fatty-acid-CoA ligase (lauric acid)
  3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 6 morecytosol

• 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. long-chain-fatty-acid-CoA ligase (lauric acid)
  3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 6 morecytosol

• O-dodecanoyl-R-carnitineReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. long-chain-fatty-acid-CoA ligase (lauric acid)
  3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)

  Catalysed by ALDH3A2, SLC27A2, ACSL4, ACSL3 and 8 morecytosolOne of 4 routes

• (11Z,14Z)-eicosadienoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes

• (17Z)-hexacosenoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes

• (7Z,10Z,13Z,16Z)-docosatetraenoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes

• (5Z,8Z,11Z)-eicosatrienoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes

• tricosanoateReach from here →
  1. dodecanoate + NADH + 2 H(+) = dodecanal + NAD(+) + H2O
  2. (10Z)-heptadecenoic acid formation
  3. (10Z)-heptadecenoic acid formation

  Catalysed by ALDH3A2cytosol, extracellular spaceOne of 12 routes