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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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lactate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

9 compounds within 3 steps: 4 in 1, 1 in 2, 4 in 3

Does it reach a compound?

One step

N(2)-(1-hydroxy-2-oxopropyl)-dGTPReach from here →
1. N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
Catalysed by PARK7
N(2)-(1-hydroxy-2-oxopropyl)-GTPReach from here →
1. N(2)-(1-hydroxy-2-oxopropyl)-GTP + H2O = lactate + GTP + H(+)
Catalysed by PARK7
N(2)-(1-hydroxy-2-oxopropyl)-GDPReach from here →
1. N(2)-(1-hydroxy-2-oxopropyl)-GDP + H2O = lactate + GDP + H(+)
Catalysed by PARK7
N(2)-(1-hydroxy-2-oxopropyl)-GMPReach from here →
1. N(2)-(1-hydroxy-2-oxopropyl)-GMP + H2O = lactate + GMP + H(+)
Catalysed by PARK7

Two steps

dGTPReach from here →
1. N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
2. N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
Catalysed by PARK7

Three steps

N(2)-(1-hydroxy-2-oxoethyl)-dGTPReach from here →
Catalysed by PARK7
2'-deoxyguanosineReach from here →
Catalysed by PARK7, SAMHD1

Reach from here →

N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
dGTP + H2O = 2'-deoxyguanosine + triphosphate + H(+)

Catalysed by PARK7, SAMHD1

dGMPReach from here →

N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
N(2)-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H(+)
dGTP + H2O = dGMP + diphosphate + H(+)

Catalysed by PARK7, NUDT15