formaldehyde

Three steps

• an S-substituted glutathioneReach from here →
  1. alcohol dehydrogenase (formaldehyde)
  2. S-formylglutathione + H2O = formate + glutathione + H(+)
  3. RX + glutathione = an S-substituted glutathione + a halide anion + H(+)

  Catalysed by ADH1C, ADH1A, ADH5, ADH6 and 26 morecytosolOne of 2 routes

• (13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
  1. alcohol dehydrogenase (formaldehyde)
  2. S-formylglutathione + H2O = formate + glutathione + H(+)
  3. (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione = (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O

  Catalysed by ADH1C, ADH1A, ADH5, ADH6 and 7 morecytosol

• taurochenodeoxycholateReach from here →
  1. alcohol dehydrogenase (formaldehyde)
  2. S-Formylglutathione hydrolase
  3. solute carrier organic anion transporter (GSH)

  Catalysed by ADH1C, ADH1A, ADH5, ADH6 and 6 morecytosol, extracellular spaceOne of 3 routes