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melatonin/Finding

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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.

  • melatonin — no detected effect on all-cause mortality

    Evidence strength: moderate.FindingNull resultreplicated ×2
    “Despite the lower mortality rate in the melatonin recipients compared to the placebo recipients during the 28-day follow-up, no statistically significant difference was observed between the study groups (p value = 0.51).”
    Quoted verbatim from A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial..
    Study
    RCT
    Duration
    5 days
    Dose
    50 mg as oral solution at 9 p.m. for five consecutive nights
    Population
    Adults aged 18-75 with early septic shock in a single ICU, all receiving standard-of-care septic shock treatment in both arms; 28-day all-cause mortality

    A pilot study on the melatonin treatment in patients with early septic shock: results of a single-center randomized controlled trial.2022PMID:3446895910.1007/s11845-021-02758-1Permalink

To cite this finding: https://catalystproject.ai/e/01M5JVZV3PFJT8W5ZGDGZHGT1X

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