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calcium carbonateFinding/e/01M2T2CJCYKMP2TVV6PY7HAH81

Calcium carbonate depletes dopamine

lowersInsufficient evidenceFinding

01 · The sentence it was drawn from

“Calcium carbonate supplementation decreased the dopamine content in the basal ganglia, including the striatum and substantia nigra, and the number of tyrosine hydroxylase-positive neurons in the substantia nigra.”
Quoted verbatim from Calcium carbonate supplementation causes motor dysfunction. · PMID 35584940 · 2022
↓ LOWERED– NO EFFECT↑ RAISED◇ OTHER
dopamine · this finding in ember among the 1 finding on it, in bands by direction at evidence strength

Findingcalcium carbonate

Dopamine

depletes

Effect as reported

not reported

Who
Mice fed diets containing 0.6% or 1.0% calcium carbonate for eight weeks; basal ganglia (striatum and substantia nigra) tissue
Dose studied
0.6% or 1.0% calcium carbonate in diet for eight weeks

Insufficient evidencePMID 35584940 · 2022

02 · The finding

Compound

calcium carbonate

Dose studied

0.6% or 1.0% calcium carbonate in diet for eight weeks

depletes

Insufficient

Mechanistic inference, no evidence found, or evidence weakened below very limited

Endpoint

dopamine

Effect as reported

not reported

Population

Mice fed diets containing 0.6% or 1.0% calcium carbonate for eight weeks; basal ganglia (striatum and substantia nigra) tissue

Study
animal · not in humans
Participants
not reported
Duration
8 weeks
Kind
Finding Reported directly by a cited source.

Evidence, by weight

  • strong
  • moderate
  • limited
  • very limited
  • insufficientthis finding

03 · The paper

Experimental animals · 2022

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M2T2CJCYKMP2TVV6PY7HAH81