Skip to content
Catalyst
Sign in

PapersPMID:35584940

Calcium carbonate supplementation causes motor dysfunction.

Experimental animals2022The record ↗

01 · finding
1
02 · compound
1
03 · endpoint
1
04 · null
0
  1. Finding, insufficient evidencelowersdopamine

What moved

1 findingHow to read these marks →
  • calcium carbonate — depletes dopamine

    insufficientFinding

    “Calcium carbonate supplementation decreased the dopamine content in the basal ganglia, including the striatum and substantia nigra, and the number of tyrosine hydroxylase-positive neurons in the substantia nigra.”
    Quoted verbatim from Calcium carbonate supplementation causes motor dysfunction..
    Study
    animal · not in humans
    Duration
    8 weeks
    Dose studied
    0.6% or 1.0% calcium carbonate in diet for eight weeks
    Population
    Mice fed diets containing 0.6% or 1.0% calcium carbonate for eight weeks; basal ganglia (striatum and substantia nigra) tissue

    Permalink

Study record

Design
animal study, in vivo
Species
animal
Population
male ICR mice fed diets containing 0.6% or 1.0% calcium carbonate for eight weeks
Participants
not recorded
Comparator
another dose / not stated in the paper
Duration
56 days
Endpoints
6
Record
extracted
Readings recorded
2