Proteins/UNIPROT:Q9HD89

RETN

ProteinUNIPROT:Q9HD89

Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells..

Function from UniProtKB (Q9HD89), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

18 statements

18 statements · 4 reference databases · Subject: RETN · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

VNN2 covaries with RETNProteinHetionet hetionet:covaries:56729-8875Inferred only
ZNF34 covaries with RETNProteinHetionet hetionet:covaries:56729-80778Inferred only
A2M interacts with RETNProteinHetionet hetionet:interacts:2-56729Inferred only
SF3A2 interacts with RETNProteinHetionet hetionet:interacts:56729-8175Inferred only
RETN participates in AdipogenesisPathwayWikiPathways WP236Inferred only
RETN participates in FOXO-mediated transcriptionPathwayReactome R-HSA-9614085Inferred only
RETN participates in FOXO-mediated transcription of oxidative stress, metabolic and neuronal genesPathwayReactome R-HSA-9615017Inferred only
RETN participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
RETN participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
RETN participates in Hallmark of cancer sustaining proliferative signalingPathwayWikiPathways WP5475Inferred only
RETN participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
RETN participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only

Show the remaining 6

RETN participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
RETN participates in Resistin as a regulator of inflammationPathwayWikiPathways WP4481Inferred only
RETN participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
RETN regulates negative regulation of feeding behaviorBiological processgene ontology Q9HD89|GO:2000252Inferred only
RETN regulates positive regulation of progesterone secretionBiological processgene ontology Q9HD89|GO:2000872Inferred only
RETN regulates positive regulation of synaptic transmissionBiological processgene ontology Q9HD89|GO:0050806Inferred only

Other names

8 names

Resolves to: RETN

Also called: Adipose tissue-specific secretory factorADSFC/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich proteinCysteine-rich secreted protein A12-alpha-like 2Cysteine-rich secreted protein FIZZ3FIZZ3HXCP1RSTN

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