Compound
N-(hexanoyl)sphing-4-enine
An N-acylsphingosine consisting of sphing-4-enine bearing a hexanoyl group on nitrogen.
Definition from ChEBI (CHEBI:63867), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound
- Formula
- C24H47NO3
- Mass
- 397.644 g/mol
- Charge
- 0
- InChIKey
- NPRJSFWNFTXXQC-QFWQFVLDSA-N
- SMILES
- CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCC
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- ASAH1ProteinUNIPROT:Q13510substrate ofInferred only26 paths26 endpoints
- CERKProteinUNIPROT:Q8TCT0substrate ofInferred only12 paths12 endpoints
- AGKProteinUNIPROT:Q53H12substrate ofInferred only9 paths9 endpoints
- ASAH2ProteinUNIPROT:Q9NR71substrate ofInferred only7 paths7 endpoints
- ACER2ProteinUNIPROT:Q5QJU3substrate ofInferred only4 paths4 endpoints
- FADS3ProteinUNIPROT:Q9Y5Q0substrate ofInferred only1 path1 endpoint
What the reference databases state
Statements
7 statements
7 statements · 1 reference database · Subject: N-(hexanoyl)sphing-4-enine · Sources: Rhea
- N-(hexanoyl)sphing-4-enine is converted to N-hexanoylsphing-4-enine 1-phosphateCompoundRhea RHEA:43312Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of ACER2ProteinRhea RHEA:41295Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of AGKProteinRhea RHEA:43312Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of ASAH1ProteinRhea RHEA:41295Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of ASAH2ProteinRhea RHEA:41295Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of CERKProteinRhea RHEA:43312Inferred only
- N-(hexanoyl)sphing-4-enine is a substrate of FADS3ProteinRhea RHEA:63940Inferred only
Reactions
3 reactions
N-(hexanoyl)sphing-4-enine+waterhexanoate+sphing-4-enine
Catalysed by ASAH1 or ACER2 or ASAH2
Reaction pageLeft to rightBalanced
Rhea RHEA:41295CC BY 4.0Reference data
N-(hexanoyl)sphing-4-enine+ATP(4-)N-hexanoylsphing-4-enine 1-phosphate+ADP(3-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:43312CC BY 4.0Reference data
N-(hexanoyl)sphing-4-enine+2Fe(II)-[cytochrome b5]+dioxygen+2hydronN-hexanoyl-sphinga-4E,14Z-dienine+2Fe(III)-[cytochrome b5]+2water
Catalysed by FADS3
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:63940CC BY 4.0Reference data
Other names
9 names
Resolves to: N-(hexanoyl)sphing-4-enine
- Also called
- C(6)-ceramideC6 ceramideC6-CerC6-ceramideCer(d18:1(4E)/6:0)Cer(d18:1/6:0)D-erythro-N-hexanoylsphingosineN-(hexanoyl)-sphing-4-enineN-hexanoyl-D-erythro-sphingosine