Compound
leukotriene E4
A biologically active principle of srs-a that is formed from leukotriene D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990)
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C23H36NO5S
- Mass
- 438.61 g/mol
- Charge
- -1
- InChIKey
- OTZRAYGBFWZKMX-FRFVZSDQSA-M
- SMILES
- CCCCC/C=CC/C=CC=CC=C[C@@H](SC[C@H]([NH3+])C(=O)[O-])[C@@H](O)CCCC(=O)[O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
2 statements
2 statements · 1 reference database · Subject: leukotriene E4 · Sources: Rhea
- leukotriene E4 is transported by ABCC2ProteinRhea RHEA:86955Inferred only
- leukotriene E4 is transported by SLCO1B1ProteinRhea RHEA:72747Inferred only
Reactions
4 reactions
leukotriene E4+NADPH(4-)+dioxygen+hydronCHEBI:58584+NADP(3-)+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:24120CC BY 4.0Reference data
leukotriene D4+waterleukotriene E4+glycine
Reaction pageLeft to rightBalanced
Rhea RHEA:48616CC BY 4.0Reference data
Transported by SLCO1B1
Reaction pageDirection not assertedBalanced
Rhea RHEA:72747CC BY 4.0Reference data
leukotriene E4+ATP(4-)+waterleukotriene E4+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC2
Reaction pageLeft to rightBalanced
Rhea RHEA:86955CC BY 4.0Reference data
Where it reaches
1 system, 4 regions, 6 tissues, 8 transporter routes — routes, not measurements: transporters known to carry leukotriene E4 are expressed there, and no source reports it arriving.
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Other names
4 names
Resolves to: leukotriene E4
- Also called
- leukotriene E4 anionLTDE4
- Systematic name
- (5S,6R,7E,9E,11Z,14Z)-6-(cysteinium-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoic acidS-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinium