Compound

7-dehydrocholesterol

CHEBI:17759ChEBI

Structure

2D depiction · 3D model shown

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A generated conformer of 7-dehydrocholesterol — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C27H44O
Mass: 384.648 g/mol
Charge: 0
InChIKey: UCTLRSWJYQTBFZ-DDPQNLDTSA-N
SMILES: [H][C@@]12CC[C@]([H])([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])C2=CC=C2C[C@@H](O)CC[C@@]21C
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Statements

14 statements

14 statements · 2 reference databases · Subject: 7-dehydrocholesterol · Sources: Human-GEM, Rhea

Order

7-dehydrocholesterol is converted to CHEBI:1307929CompoundHuman-GEM MAR00228Inferred only
7-dehydrocholesterol is converted to CHEBI:1307929CompoundHuman-GEM MAR01565Inferred only
7-dehydrocholesterol is converted to CHEBI:283119CompoundHuman-GEM MAR02114Inferred only
cholesterol is converted to 7-dehydrocholesterolCompoundRhea RHEA:23984Inferred only
7-dehydrocholesterol is converted to cholesterolCompoundRhea RHEA:23984Inferred only
lathosterol is converted to 7-dehydrocholesterolCompoundHuman-GEM MAR01510Inferred only
lathosterol is converted to 7-dehydrocholesterolCompoundHuman-GEM MAR01557Inferred only
lathosterol is converted to 7-dehydrocholesterolCompoundHuman-GEM MAR01558Inferred only
7-dehydrocholesterol is converted to previtamin D3CompoundHuman-GEM MAR08011Inferred only
previtamin D3 is converted to 7-dehydrocholesterolCompoundHuman-GEM MAR08011Inferred only
7-dehydrocholesterol is metabolised by CYP27A1ProteinHuman-GEM MAR01531Inferred only
7-dehydrocholesterol is a substrate of DHCR7ProteinHuman-GEM MAR01565Inferred only

Show the remaining 2

7-dehydrocholesterol is a substrate of DHCR7ProteinRhea RHEA:23984Inferred only
7-dehydrocholesterol is a substrate of DHCR7ProteinHuman-GEM MAR00228Inferred only

Reactions

24 reactions

7-dehydrocholesterol7-dehydrocholesterol
Reaction pageReversibleBalancedGO:0005783, GO:0005829
Human-GEM MAR00054CC BY 4.0Reference data
proton+NADPH(4-)+7-dehydrocholesterolCHEBI:1307929+NADP(3-)
Catalysed by DHCR7
Reaction pageLeft to rightBalancedEC 1.3.1.21GO:0005783
Human-GEM MAR00228CC BY 4.0Reference data
proton+lathosterol+NADPH(4-)+dioxygen2water+NADP(3-)+7-dehydrocholesterol
Catalysed by SC5D or CYP7A1
Reaction pageLeft to rightBalancedEC 1.14.19.20GO:0005783
Human-GEM MAR01510CC BY 4.0Reference data
proton+NADH(2-)+dioxygen+7-dehydrocholesterolMAM00624c+water+NAD(+)
Catalysed by CYP27A1
Reaction pageLeft to rightBalancedEC 1.14.15.15GO:0005829
Human-GEM MAR01531CC BY 4.0Reference data
proton+lathosterol+NADH(2-)+dioxygen2water+NAD(+)+7-dehydrocholesterol
Catalysed by SC5D
Reaction pageLeft to rightBalancedEC 1.14.19.20GO:0005829
Human-GEM MAR01557CC BY 4.0Reference data
proton+lathosterol+NADPH(4-)+dioxygen2water+NADP(3-)+7-dehydrocholesterol
Catalysed by SC5D
Reaction pageLeft to rightBalancedEC 1.14.19.20GO:0005829
Human-GEM MAR01558CC BY 4.0Reference data
proton+NADPH(4-)+7-dehydrocholesterolCHEBI:1307929+NADP(3-)
Catalysed by DHCR7
Reaction pageLeft to rightBalancedEC 1.3.1.21GO:0005829
Human-GEM MAR01565CC BY 4.0Reference data
7-dehydrocholesterolCHEBI:283119
Reaction pageLeft to rightBalancedGO:0005829
Human-GEM MAR02114CC BY 4.0Reference data
previtamin D37-dehydrocholesterol
Reaction pageReversibleBalancedGO:0005829
Human-GEM MAR08011CC BY 4.0Reference data
ATP+water+7-dehydrocholesterolADP+proton+phosphate(3-)+7-dehydrocholesterol
Reaction pageLeft to rightBalancedEC 3.1.1.4GO:0005829, GO:0005615
Human-GEM MAR09988CC BY 4.0Reference data
7-dehydrocholesterol7-dehydrocholesterol
Reaction pageReversibleBalancedEC 3.1.1.4GO:0005829, GO:0005615
Human-GEM MAR09989CC BY 4.0Reference data
7-dehydrocholesterol
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR10195CC BY 4.0Reference data

Show the remaining 12

Other names

11 names

Resolves to: 7-dehydrocholesterol

Also called: (3beta)-cholesta-5,7-dien-3-ol(3β)-cholesta-5,7-dien-3-ol5,7-cholestadien-3-beta-ol5,7-cholestadien-3-β-ol5,7-cholestadien-3beta-ol5,7-cholestadien-3β-ol7-DHCProvitamin D3ST 27:2;O
Systematic name: cholesta-5,7-dien-3beta-olcholesta-5,7-dien-3β-ol