Papers/PMID:42613907
Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.
Molecular nutrition & food research2026The record
3 findings · 1 compound · 3 endpoints · 3 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
3 findings
titanium dioxide — no detected effect on C-reactive protein concentration
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“Following 2 weeks of dietary E171 exposure, no statistically significant difference in hs‐CRP levels (p‐value: 0.0755) was detected, although a trend toward an increase was observed (Figure.”
Quoted verbatim from Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.. - Study
- crossover
- Duration
- 14 days
- Dose
- 2 mg/kg body weight/day of E171 for 2 weeks
- Population
- 31 healthy adults
Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.2026PMID:42613907Permalink
titanium dioxide — no detected effect on total antioxidant capacity
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“No statistically significant difference was detected between the control and E171‐exposed groups in the TEAC or TCA‐TEAC assays (Figure.”
Quoted verbatim from Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.. - Study
- crossover
- Duration
- 14 days
- Dose
- 2 mg/kg body weight/day of E171 for 2 weeks
- Population
- 31 healthy adults
Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.2026PMID:42613907Permalink
titanium dioxide — no detected effect on tumour necrosis factor alpha concentration
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“Pro‐inflammatory cytokines, including interleukin (IL)‐1β, IL‐6, IL‐8, tumor necrosis factor‐α (TNF‐α), and interferon‐γ (IFN‐γ), showed no statistically significant differences between CTRL and E171 conditions.”
Quoted verbatim from Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.. - Study
- crossover
- Duration
- 14 days
- Dose
- 2 mg/kg body weight/day of E171 for 2 weeks
- Population
- 31 healthy adults
Dietary Titanium Dioxide (E171) Alters the Colon Transcriptome-Evidence From a Human Dietary Intervention Study.2026PMID:42613907Permalink