Papers/PMID:41847903
Role of melatonin for prevention of necrotizing enterocolitis in preterm infants: a randomized controlled trial.
Journal of tropical pediatrics2026The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
melatonin — decreases tumour necrosis factor alpha concentration
Evidence strength: very limited.Finding“Enteral melatonin significantly reduced NEC incidence and mortality, accelerated achievement of full enteral feeding, and lowered TNF-α levels in preterm neonates with FI.”
Quoted verbatim from Role of melatonin for prevention of necrotizing enterocolitis in preterm infants: a randomized controlled trial.. - Study
- RCT
- Dose
- two doses of 10 mg each, 1 h apart
- Population
- preterm neonates with feeding intolerance (FI); enteral melatonin plus conventional therapy vs conventional therapy alone, measured 72 h posttreatment
Role of melatonin for prevention of necrotizing enterocolitis in preterm infants: a randomized controlled trial.2026PMID:4184790310.1093/tropej/fmag020Permalink