Papers/PMID:41254027
Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.
Scientific reports2025The record
4 findings drawn from this paper, on 1 compound across 4 endpoints.
What it reported
How to read these marksWhat moved
4 findings
all-cis-5,8,11,14,17-icosapentaenoic acid — decreases HOMA-IR
Well establishedGrade A, Well established. Replicated human trial evidence, consistent direction.Finding“Insulin resistance (HOMA-IR) significantly decreased in the EPA-rich fish oil than the controls (p = 0.001).”
Quoted verbatim from Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.. - Study
- RCT
- Participants
- 24
- Duration
- 3 weeks
- Dose
- 1.5 g/day EPA as EPA-rich fish oil capsules (500 mg EPA per capsule, three times daily with meals)
- Population
- Hospitalised adults aged 18-65 with non-severe burns covering less than 20% of total body surface area, able to take more than 90% of their daily calorie requirement by mouth, without diabetes, organ failure, cancer or immune disorder; both the EPA arm and the control arm also received 600 mg/day DHA.
Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.2025PMID:41254027
all-cis-5,8,11,14,17-icosapentaenoic acid — increases serum albumin
Well establishedGrade A, Well established. Replicated human trial evidence, consistent direction.Finding“Serum albumin was significantly higher in the EPA-rich fish oil group than the controls (p = 0.03), however this difference was not clinically significant.”
Quoted verbatim from Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.. - Study
- RCT
- Participants
- 24
- Duration
- 3 weeks
- Dose
- 1.5 g/day EPA as EPA-rich fish oil capsules (500 mg EPA per capsule, three times daily with meals)
- Population
- Hospitalised adults aged 18-65 with non-severe burns covering less than 20% of total body surface area, able to take more than 90% of their daily calorie requirement by mouth, without diabetes, organ failure, cancer or immune disorder; both the EPA arm and the control arm also received 600 mg/day DHA.
Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.2025PMID:41254027
all-cis-5,8,11,14,17-icosapentaenoic acid — decreases erythrocyte sedimentation rate
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Finding“Serum ESR and CRP levels significantly decreased in the EPA-rich fish oil (p < 0.001).”
Quoted verbatim from Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.. - Study
- RCT
- Participants
- 24
- Duration
- 3 weeks
- Dose
- 1.5 g/day EPA as EPA-rich fish oil capsules (500 mg EPA per capsule, three times daily with meals)
- Population
- Hospitalised adults aged 18-65 with non-severe burns covering less than 20% of total body surface area, able to take more than 90% of their daily calorie requirement by mouth, without diabetes, organ failure, cancer or immune disorder; both the EPA arm and the control arm also received 600 mg/day DHA.
Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.2025PMID:41254027
all-cis-5,8,11,14,17-icosapentaenoic acid — decreases C-reactive protein concentration
LikelyGrade B, Likely. Human evidence, limited replication or design limits.Finding“Serum ESR and CRP levels significantly decreased in the EPA-rich fish oil (p < 0.001).”
Quoted verbatim from Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.. - Study
- RCT
- Participants
- 24
- Duration
- 3 weeks
- Dose
- 1.5 g/day EPA as EPA-rich fish oil capsules (500 mg EPA per capsule, three times daily with meals)
- Population
- Hospitalised adults aged 18-65 with non-severe burns covering less than 20% of total body surface area, able to take more than 90% of their daily calorie requirement by mouth, without diabetes, organ failure, cancer or immune disorder; both the EPA arm and the control arm also received 600 mg/day DHA.
Eicosapentaenoic acid decreases inflammation and improves glucose homeostasis in patients with burns: a randomized clinical trial.2025PMID:41254027