Papers/PMID:41063466
Effect of Vitamin E on Serum Adiponectin and Leptin in Adults: A Systematic Review and Meta-analysis.
Journal of dietary supplements2025The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
α-tocopherol — no detected effect on serum leptin
Evidence strength: very limited.FindingNull result“The pooled analysis of 10 RCTs (14 effect sizes) showed that vitamin E supplementation did not significantly alter serum adiponectin (WMD: 0.67 ng/mL; 95% CI: [-0.11 - 1.44]; p = 0.093) or leptin levels (WMD: -3.60 ng/mL; 95% CI: [-7.45 - 0.25]; p = 0.067).”
Quoted verbatim from Effect of Vitamin E on Serum Adiponectin and Leptin in Adults: A Systematic Review and Meta-analysis.. - Study
- meta-analysis
- Population
- Adults; pooled randomised controlled trials of oral vitamin E supplementation (overall estimate, all subgroups combined)
Effect -3.6 mean difference, 95% CI -7.45 to 0.25
Effect of Vitamin E on Serum Adiponectin and Leptin in Adults: A Systematic Review and Meta-analysis.2025PMID:4106346610.1080/19390211.2025.2561143Permalink
α-tocopherol — no detected effect on serum adiponectin
Evidence strength: very limited.FindingNull resultreplicated ×1“The pooled analysis of 10 RCTs (14 effect sizes) showed that vitamin E supplementation did not significantly alter serum adiponectin (WMD: 0.67 ng/mL; 95% CI: [-0.11 - 1.44]; p = 0.093) or leptin levels (WMD: -3.60 ng/mL; 95% CI: [-7.45 - 0.25]; p = 0.067).”
Quoted verbatim from Effect of Vitamin E on Serum Adiponectin and Leptin in Adults: A Systematic Review and Meta-analysis.. - Study
- meta-analysis
- Population
- Adults; pooled randomised controlled trials of oral vitamin E supplementation (overall estimate, all subgroups combined)
Effect 0.67 mean difference, 95% CI -0.11 to 1.44
Effect of Vitamin E on Serum Adiponectin and Leptin in Adults: A Systematic Review and Meta-analysis.2025PMID:4106346610.1080/19390211.2025.2561143Permalink