Papers/PMID:40048726
Different doses of theacrine do not improve 4 km cycling time trial performance.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2025The record
3 findings · 1 compound · 3 endpoints · 1 null
What it reported
How to read these marksWhat moved
2 findings
1,3,7,9-tetramethyluric acid — increases systolic blood pressure (setting unspecified)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“However, the intake of theacrine at the dose of 6 mg·kg-1 increased resting systolic and diastolic blood pressure (p < 0.05).”
Quoted verbatim from Different doses of theacrine do not improve 4 km cycling time trial performance.. - Study
- crossover
- Dose
- single dose of 6 mg/kg body mass anhydrous theacrine
- Population
- 19 cyclists (11 men, 8 women); 6 mg/kg dose stratum only, resting blood pressure
Different doses of theacrine do not improve 4 km cycling time trial performance.2025PMID:40048726Permalink
1,3,7,9-tetramethyluric acid — increases diastolic blood pressure (setting unspecified)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“However, the intake of theacrine at the dose of 6 mg·kg-1 increased resting systolic and diastolic blood pressure (p < 0.05).”
Quoted verbatim from Different doses of theacrine do not improve 4 km cycling time trial performance.. - Study
- crossover
- Dose
- single dose of 6 mg/kg body mass anhydrous theacrine
- Population
- 19 cyclists (11 men, 8 women); 6 mg/kg dose stratum only, resting blood pressure
Different doses of theacrine do not improve 4 km cycling time trial performance.2025PMID:40048726Permalink
What did not
1 finding
1,3,7,9-tetramethyluric acid — no detected effect on time-trial completion time
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“No significant differences (p < 0.05) were observed in time to cover the 4 km cycling time trial between the placebo, 3 mg·kg-1 of theacrine, and 6 mg·kg-1 of theacrine conditions.”
Quoted verbatim from Different doses of theacrine do not improve 4 km cycling time trial performance.. - Study
- crossover
- Dose
- single dose of 3 or 6 mg/kg body mass anhydrous theacrine before each trial
- Population
- 19 cyclists (11 men, 8 women); 4 km cycling time trial after placebo, 3 mg/kg or 6 mg/kg anhydrous theacrine
Different doses of theacrine do not improve 4 km cycling time trial performance.2025PMID:40048726Permalink