Papers/PMID:39509416
The Optimal Dosage and Duration of Metformin for Prevention and Treatment of Antipsychotic-Induced Weight Gain: An Updated Systematic Review and Meta-Analysis.
Schizophrenia bulletin2025The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
metformin — decreases body mass index
Evidence strength: very limited.Findingreplicated ×1“Additionally, metformin use resulted in a marked decrease in body mass index [-1.24 kg/m2 (95% CI: -1.70 to -0.77)].”
Quoted verbatim from The Optimal Dosage and Duration of Metformin for Prevention and Treatment of Antipsychotic-Induced Weight Gain: An Updated Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Patients receiving second-generation antipsychotics with antipsychotic-induced weight gain, pooled from double-blind placebo-controlled trials
The Optimal Dosage and Duration of Metformin for Prevention and Treatment of Antipsychotic-Induced Weight Gain: An Updated Systematic Review and Meta-Analysis.2025PMID:3950941610.1093/schbul/sbae173Permalink