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Papers/PMID:38245691

Effects of calcium supplementation on changes in the IL2, IL4, IL6, IL10 axes and oxidative stress in pregnant women at risk for pre-eclampsia.

BMC pregnancy and childbirth2024The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • Ca(2+) — increases malondialdehyde (circulating)

    Evidence strength: moderate.Finding
    “There were significant differences (p < 0.005) between the groups in the TBARS pro-oxidant marker, with an increase for the 500 mg calcium/day and 1,500 mg calcium/day groups when compared to the placebo group.”
    Quoted verbatim from Effects of calcium supplementation on changes in the IL2, IL4, IL6, IL10 axes and oxidative stress in pregnant women at risk for pre-eclampsia..
    Study
    RCT
    Duration
    6 weeks
    Dose
    500 mg or 1,500 mg elemental calcium per day, oral tablets, from the 20th gestational week; 6 weeks of sampling
    Population
    Primigravid pregnant women at high risk of pre-eclampsia (gestational hypertension, overweight/obesity, low dietary calcium intake), both calcium dose groups compared with placebo

    Effects of calcium supplementation on changes in the IL2, IL4, IL6, IL10 axes and oxidative stress in pregnant women at risk for pre-eclampsia.2024PMID:3824569110.1186/s12884-023-06235-8Permalink