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Papers/PMID:37831676

Association of the dietary copper intake with all-cause and cardiovascular mortality: A prospective cohort study.

PloS one2023The record

2 findings · 1 compound · 2 endpoints · 1 null

What it reported

How to read these marks

What moved

1 finding

  • Cu(2+) — decreases all-cause mortality

    Evidence strength: limited.Findingreplicated ×1
    “Elevated Cu intake was shown to be related to a decreased risk of all-cause mortality after accounting for lab test results, drugs, medical history, behavior, anthropometric variables, socioeconomics, and demographics (Model 5).”
    Quoted verbatim from Association of the dietary copper intake with all-cause and cardiovascular mortality: A prospective cohort study..
    Study
    cohort
    Dose
    dietary copper intake quartiles, Q1 <0.8 mg/d to Q4 >=1.5 mg/d
    Population
    US NHANES 2001-2018 adults aged 20 years and above (n=39,784, nationally representative weighted sample); dietary copper from two 24-hour recalls, quartile analysis, mortality follow-up through 2019

    Association of the dietary copper intake with all-cause and cardiovascular mortality: A prospective cohort study.2023PMID:3783167610.1371/journal.pone.0292759Permalink

What did not

1 finding

  • Cu(2+) — no detected effect on cardiovascular mortality

    Evidence strength: moderate.FindingNull result
    “A comparative analysis of the lowest dietary Cu intake quartile illustrated that the weighted multivariate HRs for death from cardiovascular-related causes were 0.92 (0.78–1.08) for Q2, 0.95 (0.80–1.13) for Q3, and 0.80 (0.63–1.02) for Q4, and the association is not significant (P for trend = 0.095; Table 2).”
    Quoted verbatim from Association of the dietary copper intake with all-cause and cardiovascular mortality: A prospective cohort study..
    Study
    cohort
    Dose
    dietary copper intake quartiles, Q1 <0.8 mg/d to Q4 >=1.5 mg/d
    Population
    US NHANES 2001-2018 adults aged 20 years and above (n=39,784, nationally representative weighted sample); dietary copper from two 24-hour recalls, quartile analysis, fully adjusted model

    Association of the dietary copper intake with all-cause and cardiovascular mortality: A prospective cohort study.2023PMID:3783167610.1371/journal.pone.0292759Permalink