Papers/PMID:37602580
Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.
The Indian journal of medical research2023The record
2 findings · 1 compound · 2 endpoints · 2 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
2 findings
Ca(2+) — no detected effect on hip fracture incidence
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The association between calcium administration and hip fracture [risk ratio (RR) 1.56; 95% confidence interval (CI), 0.91 to 2.69, I2=28%; P=0.11], vertebral fracture (RR 0.95; 95% CI, 0.82 to 1.10, I2=0%; P=0.49) or other fractures (RR 0.83; 95% CI 0.65 to 1.06, I2=0%; P=0.14) was not significant in comparison to either no treatment or placebo administration.”
Quoted verbatim from Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.. - Study
- meta-analysis
- Population
- Adults older than 50 years with a previous history of fracture; pooled randomised trials of calcium supplementation against placebo or no treatment
Effect 1.56 risk ratio, 95% CI 0.91 to 2.69
Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.2023PMID:37602580Permalink
Ca(2+) — no detected effect on vertebral fracture incidence
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“The association between calcium administration and hip fracture [risk ratio (RR) 1.56; 95% confidence interval (CI), 0.91 to 2.69, I2=28%; P=0.11], vertebral fracture (RR 0.95; 95% CI, 0.82 to 1.10, I2=0%; P=0.49) or other fractures (RR 0.83; 95% CI 0.65 to 1.06, I2=0%; P=0.14) was not significant in comparison to either no treatment or placebo administration.”
Quoted verbatim from Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.. - Study
- meta-analysis
- Population
- Adults older than 50 years with a previous history of fracture; pooled randomised trials of calcium supplementation against placebo or no treatment
Effect 0.95 risk ratio, 95% CI 0.82 to 1.1
Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.2023PMID:37602580Permalink