PapersPMID:37447322
Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.
- findings
- 2
- compound
- 1
- endpoints
- 2
- Study, every finding
- RCT · 3 months
- Dose studied, every finding
- 10 tablets per day, 200 mg MSM per tablet, vs lactose tablets
- Population, every finding
- Healthy Japanese adults with mild knee pain (Kellgren-Lawrence grade 0 or 1); per-protocol set; change from baseline at each visit up to 12 weeks
No finding here moved its endpoint.
What did not
How to read these marks →“There was also no significant difference in the amount of change in IL-1 beta, IL-6, and Hs-CRP between the MSM and placebo groups during any week of comparison (Supplementary Table S2).”
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- healthy Japanese participants with mild knee pain, Kellgren-Lawrence grade 0 or 1
- Participants
- 88
- Comparator
- placebo
- Duration
- 84 days
- Endpoints measured
- 14