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PapersPMID:37170623

Garlic supplementation attenuates cycling exercise-induced oxidative inflammation but fails to improve time trial performance in healthy adults.

Journal of the International Society of Sports Nutrition2023The record ↗

findings
3
compound
1
endpoints
3
no difference found
1
PMID:37170623
  1. Finding, moderate evidencelowersTumour necrosis factor alpha concentration
  2. Finding, moderate evidenceraisesTotal antioxidant capacity
  3. Finding, moderate evidenceno difference foundTime-trial completion time
Study, every finding
crossover · 4 weeks
Dose studied, every finding
1000 mg/day for 4 weeks
  • “Identically, TNF-α levels were shown to have lower levels at 10-km, and 20-km during exercise and after garlic supplementation compared to those of placebo (< 0.05).”
    Population
    Eleven healthy, physically active males in a single-blind crossover with a 28-day washout; serum TNF-α, difference at 10 km and 20 km only
  • “Figure 3(a) shows that TAC responses were significantly higher in the garlic trial compared to those in placebo before exercise and during the exercise period (< 0.05).”
    Population
    Eleven healthy, physically active males in a single-blind crossover with a 28-day washout; plasma TAC before and during a 40-km cycling bout

What did not

  • “Following 4-wks of oral supplementation, there was no significant improvement in the 40-km cycling time trial performance after garlic supplementation compared to placebo trials (garlic trial: 81.18 ± 2.12 (min); placebo trial: 84.14 ± 2.88 (min), p > 0.05).”
    Population
    Eleven healthy, physically active males in a single-blind crossover with a 28-day washout; fixed-distance 40-km cycling time trial at 50% VO2max

Study record

Design
crossover trial
Species
human
Population
Eleven physically active healthy males, single-blind crossover
Participants
11
Comparator
placebo
Duration
28 days
Endpoints measured
13