Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

Atlas Graph Access

Search the graph

Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Pathways Processes Anatomy Cell types Organisms Materials Assessments

Loading the page.

Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy Terms

Reference data under the licences listed on the attribution page.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments

How it works

Mission
Method
How to read the evidence
Sources and licences

Build on it

Access
For agents
Query the graph
Bulk export

Papers/PMID:36870101

The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.

Sleep medicine reviews2023The record

2 findings drawn from this paper, on 1 compound across 2 endpoints.

caffeine

What it reported

How to read these marks

What moved

2 findings

caffeine — decreases total sleep time
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding
“Caffeine consumption reduced total sleep time by 45 min and sleep efficiency by 7%, with an increase in sleep onset latency of 9 min and wake after sleep onset of 12 min.”
Quoted verbatim from The effect of caffeine on subsequent sleep: A systematic review and meta-analysis..
Study

meta-analysis
Population

meta-analysis of 24 studies on the effect of caffeine consumption on subsequent night-time sleep
The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.2023PMID:36870101
caffeine — increases sleep onset latency
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding
“Caffeine consumption reduced total sleep time by 45 min and sleep efficiency by 7%, with an increase in sleep onset latency of 9 min and wake after sleep onset of 12 min.”
Quoted verbatim from The effect of caffeine on subsequent sleep: A systematic review and meta-analysis..
Study

meta-analysis
Population

meta-analysis of 24 studies on the effect of caffeine consumption on subsequent night-time sleep
The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.2023PMID:36870101