Papers/PMID:35816459
Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.
The American journal of clinical nutrition2022The record
2 findings · 1 compound · 2 endpoints · 1 null
What it reported
How to read these marksWhat moved
1 finding
magnesium(2+) — decreases incidence of stroke
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.Findingreplicated ×1“However, for drinking water magnesium and stroke, the highest tertile of drinking water magnesium compared with the lowest was associated with a reduced risk of ischemic stroke (HR: 0.69; 95% CI: 0.54, 0.88), whereas the corresponding HR for hemorrhagic stroke was 0.75 (95% CI: 0.43, 1.31) (Table 5).”
Quoted verbatim from Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.. - Study
- cohort
- Dose
- drinking water magnesium, highest tertile (10.6-13.8 mg/L) vs lowest (0.6-4.5 mg/L)
- Population
- Women of the Swedish Mammography Cohort (n = 26,733) served by public drinking water; ischemic stroke subtype; highest versus lowest tertile of drinking water magnesium, model adjusted for drinking water calcium
Effect 0.69 hazard ratio, 95% CI 0.54 to 0.88
Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.2022PMID:35816459Permalink
What did not
1 finding
magnesium(2+) — no detected effect on incidence of myocardial infarction
LimitedEvidence strength: limited. Human evidence with several recorded weaknesses, or a design that tops out at limited.FindingNull result“The association of drinking water magnesium with myocardial infarction was not significant (HR: 0.91; 95% CI: 0.70, 1.20 for the highest tertile compared to the lowest; Table 5).”
Quoted verbatim from Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.. - Study
- cohort
- Dose
- drinking water magnesium, highest tertile (10.6-13.8 mg/L) vs lowest (0.6-4.5 mg/L)
- Population
- Women of the Swedish Mammography Cohort (n = 26,733) served by public drinking water; highest versus lowest tertile of drinking water magnesium, model adjusted for drinking water calcium
Effect 0.91 hazard ratio, 95% CI 0.7 to 1.2
Calcium and magnesium in drinking water and risk of myocardial infarction and stroke-a population-based cohort study.2022PMID:35816459Permalink