Papers/PMID:35436355
High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults.
Journal of pineal research2022The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
melatonin — increases total sleep time
Evidence strength: limited.Findingreplicated ×5“In the high-dose group, overall there was significantly greater sleep efficiency and TST in the melatonin condition compared with the placebo condition (see Figure 2, upper panel).”
Quoted verbatim from High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults.. - Study
- crossover
- Duration
- 12 days
- Dose
- 5.0 mg melatonin 30 minutes before bedtime for 12 nights, versus placebo for 12 nights in the other condition
- Population
- Healthy older adults (age over 55) in the high-dose (5 mg) melatonin group of a forced desynchrony crossover; polysomnography, all sleep episodes pooled across biological day and night
High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults.2022PMID:3543635510.1111/jpi.12801Industry fundedPermalink