Papers/PMID:35091276
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.
Nutrition research (New York, N.Y.)2022The record
3 findings · 1 compound · 3 endpoints · 2 null
What it reported
How to read these marksWhat moved
1 finding
astaxanthin — decreases interleukin-6 concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Findingreplicated ×1“Astaxanthin significantly reduced blood interleukin-6 concentration in T2DM patients (weighted mean difference: -0.70 pg/mL; 95% CI, -1.29 to -0.11 pg/mL; P = .02).”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- type 2 diabetes mellitus (T2DM) patients; meta-analysis subgroup within the pooled 12-RCT synthesis
Effect -0.7 mean difference, 95% CI -1.29 to -0.11
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink
What did not
2 findings
astaxanthin — no detected effect on tumour necrosis factor alpha concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“The effects of astaxanthin on blood C-reactive protein and tumor necrosis factor-α concentrations were not significant.”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults, including type 2 diabetes mellitus (T2DM) patients; meta-analysis pooling 12 RCTs
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink
astaxanthin — no detected effect on C-reactive protein concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull resultreplicated ×1“The effects of astaxanthin on blood C-reactive protein and tumor necrosis factor-α concentrations were not significant.”
Quoted verbatim from Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- adults, including type 2 diabetes mellitus (T2DM) patients; meta-analysis pooling 12 RCTs
Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials.2022PMID:35091276Permalink