Papers/PMID:33724323
Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.
JAMA2021The record
1 finding · 1 compound · 1 endpoint · 1 null
What it reported
How to read these marksEvery finding here is a null result.
What did not
1 finding
calciol — no detected effect on community-dwelling atrial fibrillation incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Among adults aged 50 years or older, treatment with EPA-DHA or vitamin D3, compared with placebo, resulted in no significant difference in the risk of incident AF over a median follow-up of more than 5 years.”
Quoted verbatim from Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.. - Study
- RCT
- Dose
- vitamin D3 2000 IU/d versus placebo, median 5.3 years of treatment and follow-up
- Population
- Community-dwelling US men and women aged 50 years or older without prior cardiovascular disease, cancer or atrial fibrillation; 2 x 2 factorial with marine omega-3 fatty acids, the omega-3 allocation balanced across the vitamin D3 and placebo comparison
Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.2021PMID:33724323Permalink