Endpoint
Community-dwelling atrial fibrillation incidence
CAT:outcome/community-atrial-fibrillation-incidencereported in proportion1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · 1 null · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| calciol | no effect | 1 | Evidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence. |
Every finding here is a null result.
Measured, no effect detected
1 finding
calciol — no detected effect on
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Among adults aged 50 years or older, treatment with EPA-DHA or vitamin D3, compared with placebo, resulted in no significant difference in the risk of incident AF over a median follow-up of more than 5 years.”
Quoted verbatim from Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.. - Study
- RCT
- Dose
- vitamin D3 2000 IU/d versus placebo, median 5.3 years of treatment and follow-up
- Population
- Community-dwelling US men and women aged 50 years or older without prior cardiovascular disease, cancer or atrial fibrillation; 2 x 2 factorial with marine omega-3 fatty acids, the omega-3 allocation balanced across the vitamin D3 and placebo comparison
Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial.2021PMID:33724323Permalink
How it is measured
Incident atrial fibrillation, new-onset or first-diagnosed, in community-dwelling general-population adults free of atrial fibrillation at baseline, ascertained by electrocardiogram, clinical diagnosis, hospital discharge coding or registry linkage over the follow-up the source states. Reported as the proportion or rate of participants developing atrial fibrillation. The ascertainment method and follow-up length are recorded with each finding.
Sources cited
1 paper
- Subject
- community-dwelling atrial fibrillation incidence
- Findings
- 1
- Papers
- 1