Papers/PMID:33321447
Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials.
Complementary therapies in clinical practice2021The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
chromium(3+) — decreases tumour necrosis factor alpha concentration
Evidence strength: very limited.Findingreplicated ×1“The pooled findings for biomarkers of inflammation showed that chromium supplementation significantly reduced serum high-sensitivity C-reactive protein (hs-CRP) (WMD: -0.87 mg/dL, 95% CI: -1.49, -0.26), and tumor necrosis factor-alpha (TNF-α) (WMD: -0.97 pg/ml; 95% CI: -1.92, -0.01) and chromium insignificantly reduced interleukin -6 (IL-6) (WMD: -0.45 pg/ml, 95% CI: -1.18, 0.29).”
Quoted verbatim from Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials.. - Study
- meta-analysis
- Population
- Pooled randomized controlled trials of chromium supplementation
Effect -0.97 mean difference, 95% CI -1.92 to -0.01
Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials.2021PMID:3332144710.1016/j.ctcp.2020.101291Permalink
chromium(3+) — decreases C-reactive protein concentration
Evidence strength: very limited.Findingreplicated ×3“The pooled findings for biomarkers of inflammation showed that chromium supplementation significantly reduced serum high-sensitivity C-reactive protein (hs-CRP) (WMD: -0.87 mg/dL, 95% CI: -1.49, -0.26), and tumor necrosis factor-alpha (TNF-α) (WMD: -0.97 pg/ml; 95% CI: -1.92, -0.01) and chromium insignificantly reduced interleukin -6 (IL-6) (WMD: -0.45 pg/ml, 95% CI: -1.18, 0.29).”
Quoted verbatim from Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials.. - Study
- meta-analysis
- Population
- Pooled randomized controlled trials of chromium supplementation
Effect -0.87 mean difference, 95% CI -1.49 to -0.26
Effect of chromium supplementation on hs-CRP, TNF-α and IL-6 as risk factor for cardiovascular diseases: A meta-analysis of randomized-controlled trials.2021PMID:3332144710.1016/j.ctcp.2020.101291Permalink