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Papers/PMID:33226265

The effect of calcium supplement intake on lipid profile: a systematic review and meta-analysis of randomized controlled clinical trials.

Critical reviews in food science and nutrition2022The record

1 finding · 1 compound · 1 endpoint

What it reported

How to read these marks

What moved

1 finding

  • Ca(2+) — decreases LDL cholesterol

    Evidence strength: very limited.Findingreplicated ×1
    “Calcium supplement intake was associated with a significant reduction in low density lipoprotein cholesterol (LDL-C) level (WMD:-0.08; 95%CI:-0.16,-0.01)(mmol/l), especially with intakes of at least 1000 mg/day (WMD:-0.13; 95%CI:-0.23,-0.03)(mmol/l), with intakes of at least 12 weeks (WMD:-0.08; 95%CI: -0.16,-0.00)(mmol/l), and in individuals without dyslipidemia (WMD:-0.15; 95%CI:-0.26,-0.04)(mmol/l).”
    Quoted verbatim from The effect of calcium supplement intake on lipid profile: a systematic review and meta-analysis of randomized controlled clinical trials..
    Study
    meta-analysis
    Population
    Participants of pooled randomized controlled trials of calcium supplementation; overall estimate, unit mmol/l

    Effect -0.08 mean difference, 95% CI -0.16 to -0.01

    The effect of calcium supplement intake on lipid profile: a systematic review and meta-analysis of randomized controlled clinical trials.2022PMID:3322626510.1080/10408398.2020.1850414Permalink