Papers/PMID:32583356
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.
European journal of clinical pharmacology2020The record
4 findings drawn from this paper, on 1 compound across 4 endpoints, 2 of them null.
What it reported
How to read these marksWhat moved
2 findings
coenzyme Q10 — increases total antioxidant capacity
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“CoQ10 supplementation, in the tested range of doses, was shown to reduce MDA concentrations, and increase TAC and antioxidant defense system enzymes.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356
coenzyme Q10 — decreases malondialdehyde (circulating)
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding“CoQ10 supplementation, in the tested range of doses, was shown to reduce MDA concentrations, and increase TAC and antioxidant defense system enzymes.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356
What did not
2 findings
coenzyme Q10 — no detected effect on catalase activity
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“However, there were no significant effects of CoQ10 on NO, GSH concentrations, or CAT activity.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356
coenzyme Q10 — no detected effect on reduced glutathione concentration
PreliminaryGrade D, Preliminary. Non-human or in vitro only.FindingNull result“However, there were no significant effects of CoQ10 on NO, GSH concentrations, or CAT activity.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356