Papers/PMID:32583356
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.
European journal of clinical pharmacology2020The record
4 findings · 1 compound · 4 endpoints · 2 null
What it reported
How to read these marksWhat moved
2 findings
coenzyme Q10 — increases total antioxidant capacity
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“CoQ10 supplementation, in the tested range of doses, was shown to reduce MDA concentrations, and increase TAC and antioxidant defense system enzymes.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356Permalink
coenzyme Q10 — decreases malondialdehyde (circulating)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“CoQ10 supplementation, in the tested range of doses, was shown to reduce MDA concentrations, and increase TAC and antioxidant defense system enzymes.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356Permalink
What did not
2 findings
coenzyme Q10 — no detected effect on catalase activity
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“However, there were no significant effects of CoQ10 on NO, GSH concentrations, or CAT activity.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356Permalink
coenzyme Q10 — no detected effect on reduced glutathione concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“However, there were no significant effects of CoQ10 on NO, GSH concentrations, or CAT activity.”
Quoted verbatim from Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.. - Study
- meta-analysis
- Population
- participants in randomized clinical trials of CoQ10 supplementation
Coenzyme Q10 supplementation and oxidative stress parameters: a systematic review and meta-analysis of clinical trials.2020PMID:32583356Permalink