PapersPMID:32544011
The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
- 01 · findings
- 3
- 02 · compound
- 1
- 03 · endpoints
- 3
- 04 · null
- 0
What it reported
How to read these marksWhat moved
3 findings
coenzyme Q10 — decreases C-reactive protein concentration
Evidence strength: very limited.Findingreplicated ×3“At the end of study, compared with pldacebo, CoQ10 supplementation resulted in significant decreases in serum levels of TNF-α (p = 0.009), hs-CRP and IL-6 (p = 0.001, p = 0.007, respectively).”
Quoted verbatim from The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 200 mg CoQ10 capsules per day, 8 weeks
- Population
- Overweight and obese women with polycystic ovary syndrome (PCOS)
The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.2021PMID:3254401110.1080/09513590.2020.1779689Permalink
coenzyme Q10 — decreases interleukin-6 concentration
Evidence strength: very limited.Findingreplicated ×1“At the end of study, compared with pldacebo, CoQ10 supplementation resulted in significant decreases in serum levels of TNF-α (p = 0.009), hs-CRP and IL-6 (p = 0.001, p = 0.007, respectively).”
Quoted verbatim from The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 200 mg CoQ10 capsules per day, 8 weeks
- Population
- Overweight and obese women with polycystic ovary syndrome (PCOS)
The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.2021PMID:3254401110.1080/09513590.2020.1779689Permalink
coenzyme Q10 — decreases tumour necrosis factor alpha concentration
Evidence strength: very limited.Findingreplicated ×2“At the end of study, compared with pldacebo, CoQ10 supplementation resulted in significant decreases in serum levels of TNF-α (p = 0.009), hs-CRP and IL-6 (p = 0.001, p = 0.007, respectively).”
Quoted verbatim from The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.. - Study
- RCT
- Duration
- 8 weeks
- Dose
- 200 mg CoQ10 capsules per day, 8 weeks
- Population
- Overweight and obese women with polycystic ovary syndrome (PCOS)
The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.2021PMID:3254401110.1080/09513590.2020.1779689Permalink
Study record
Read under: coenzyme Q10
- Design
- randomised controlled trial
- Species
- human
- Population
- overweight and obese women with polycystic ovary syndrome (PCOS)
- Participants
- not recorded
- Comparator
- not stated in the paper
- Duration
- 56 days
- Endpoints
- 6
- Record
- extracted
- Readings recorded
- 2