Papers/PMID:29347988
Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial.
BMC medicine2018The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
melatonin — decreases pittsburgh Sleep Quality Index global score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×2“Melatonin was associated with a significant and moderate reduction in PSQI global scores, indicating improved sleep quality (Table 2).”
Quoted verbatim from Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial.. - Study
- crossover
- Participants
- 33
- Duration
- 4 weeks
- Dose
- 2 mg prolonged-release melatonin (Circadin) nightly within 2 hours of sleep
- Population
- Community-dwelling adults aged 18 to 65 with chronic insomnia after mild to severe traumatic brain injury, randomised double-blind placebo-controlled crossover, 4 weeks each period
Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial.2018PMID:29347988An author is affiliated with a producerPermalink
melatonin — decreases subjective fatigue
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Findingreplicated ×2“Melatonin significantly reduced the self-reported impact of fatigue during daily activities as measured by the FSS.”
Quoted verbatim from Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial.. - Study
- crossover
- Participants
- 33
- Duration
- 4 weeks
- Dose
- 2 mg prolonged-release melatonin (Circadin) nightly within 2 hours of sleep
- Population
- Community-dwelling adults aged 18 to 65 with chronic insomnia after mild to severe traumatic brain injury, randomised double-blind placebo-controlled crossover, 4 weeks each period
Efficacy of melatonin for sleep disturbance following traumatic brain injury: a randomised controlled trial.2018PMID:29347988An author is affiliated with a producerPermalink