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Papers/PMID:28850930

Thiamine in septic shock patients with alcohol use disorders: An observational pilot study.

Journal of critical care2018The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • thiamine — decreases all-cause mortality

    Evidence strength: moderate.Findingreplicated ×9
    “We found a significantly lower mortality for those receiving thiamine compared to those not receiving thiamine (15 [44%] vs. 15 [79%], p = 0.02, Table 2).”
    Quoted verbatim from Thiamine in septic shock patients with alcohol use disorders: An observational pilot study..
    Study
    cohort
    Dose
    most commonly 100 mg per dose
    Population
    Adults with septic shock and alcohol use disorder in an ICU (retrospective, unadjusted comparison); thiamine-treated patients versus patients given no thiamine; routes pooled (68% of initial doses parenteral, remainder oral)

    Thiamine in septic shock patients with alcohol use disorders: An observational pilot study.2018PMID:2885093010.1016/j.jcrc.2017.08.022Permalink