Papers/PMID:28437264
Magnesium sulphate improves pulmonary function after video-assisted thoracoscopic surgery: A randomised double-blind placebo-controlled study.
European journal of anaesthesiology2017The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
magnesium(2+) — increases forced expiratory volume in one second (FEV1)
Evidence strength: very limited.Findingreplicated ×1“FEV1 at 24 (1.7 ± 0.6 vs. 1.3 ± 0.5 l, P = 0.033) and 48 h (1.7 ± 0.6 vs. 1.4 ± 0.5 l, P = 0.021) and FVC at 24 (2.0 ± 0.8 vs. 1.6 ± 0.6 l, P = 0.038) and 48 h (2.2 ± 0.8 vs. 1.7 ± 0.7 l, P = 0.008) after surgery were significantly greater in the Mg group.”
Quoted verbatim from Magnesium sulphate improves pulmonary function after video-assisted thoracoscopic surgery: A randomised double-blind placebo-controlled study.. - Study
- RCT
- Dose
- MgSO4 50 mg/kg IV over 10 min, then 15 mg/kg/h infusion during surgery, vs 0.9% saline
- Population
- Adults undergoing video-assisted thoracoscopic lobectomy or segmentectomy; FEV1 at 24 and 48 h after surgery (not different at 12 months)
Magnesium sulphate improves pulmonary function after video-assisted thoracoscopic surgery: A randomised double-blind placebo-controlled study.2017PMID:2843726410.1097/EJA.0000000000000641Permalink