Papers/PMID:28179205
Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.
Pharmacological research2017The record
3 findings · 1 compound · 3 endpoints
What it reported
How to read these marksWhat moved
3 findings
coenzyme Q10 — decreases interleukin-6 concentration
Evidence strength: very limited.Findingreplicated ×1“CoQ10 supplementation significantly reduced the levels of circulating CRP (WMD: -0.35mg/L, 95% CI: -0.64 to -0.05, P=0.022), IL-6 (WMD: -1.61pg/mL, 95% CI: -2.64 to -0.58, P=0.002) and TNF-α (WMD: -0.49pg/mL, 95% CI: -0.93 to -0.06, P=0.027).”
Quoted verbatim from Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- patients from randomized controlled trials of CoQ10 supplementation (disease population not specified in abstract)
Effect -1.61 mean difference, 95% CI -2.64 to -0.58
Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.2017PMID:2817920510.1016/j.phrs.2017.01.032Permalink
coenzyme Q10 — decreases tumour necrosis factor alpha concentration
Evidence strength: very limited.Findingreplicated ×2“CoQ10 supplementation significantly reduced the levels of circulating CRP (WMD: -0.35mg/L, 95% CI: -0.64 to -0.05, P=0.022), IL-6 (WMD: -1.61pg/mL, 95% CI: -2.64 to -0.58, P=0.002) and TNF-α (WMD: -0.49pg/mL, 95% CI: -0.93 to -0.06, P=0.027).”
Quoted verbatim from Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- patients from randomized controlled trials of CoQ10 supplementation (disease population not specified in abstract)
Effect -0.49 mean difference, 95% CI -0.93 to -0.06
Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.2017PMID:2817920510.1016/j.phrs.2017.01.032Permalink
coenzyme Q10 — decreases C-reactive protein concentration
Evidence strength: very limited.Findingreplicated ×3“CoQ10 supplementation significantly reduced the levels of circulating CRP (WMD: -0.35mg/L, 95% CI: -0.64 to -0.05, P=0.022), IL-6 (WMD: -1.61pg/mL, 95% CI: -2.64 to -0.58, P=0.002) and TNF-α (WMD: -0.49pg/mL, 95% CI: -0.93 to -0.06, P=0.027).”
Quoted verbatim from Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.. - Study
- meta-analysis
- Population
- patients from randomized controlled trials of CoQ10 supplementation (disease population not specified in abstract)
Effect -0.35 mean difference, 95% CI -0.64 to -0.05
Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.2017PMID:2817920510.1016/j.phrs.2017.01.032Permalink