Papers/PMID:27655440
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers.
The American journal of clinical nutrition2017The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
L-isoleucine — decreases postprandial blood glucose area under the curve
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Compared with the control, isoleucine-10g reduced the blood glucose AUC and peak blood glucose (P < 0.01), whereas effects of isoleucine-5g were NS.”
Quoted verbatim from Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers.. - Study
- crossover
- Dose
- 10 g isoleucine, single intragastric infusion, 15 min before a mixed-nutrient drink
- Population
- healthy, lean subjects; isoleucine 10 g intragastric dose (isoleucine 5 g dose was not significant)
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers.2017PMID:27655440Permalink
L-isoleucine — decreases peak postprandial blood glucose
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Compared with the control, isoleucine-10g reduced the blood glucose AUC and peak blood glucose (P < 0.01), whereas effects of isoleucine-5g were NS.”
Quoted verbatim from Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers.. - Study
- crossover
- Dose
- 10 g isoleucine, single intragastric infusion, 15 min before a mixed-nutrient drink
- Population
- healthy, lean subjects; isoleucine 10 g intragastric dose (isoleucine 5 g dose was not significant)
Intragastric administration of leucine or isoleucine lowers the blood glucose response to a mixed-nutrient drink by different mechanisms in healthy, lean volunteers.2017PMID:27655440Permalink