Papers/PMID:25329821
Calcium supplementation increases blood creatinine concentration in a randomized controlled trial.
PloS one2014The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
Ca(2+) — increases serum creatinine concentration
Evidence strength: moderate.Finding“After controlling for characteristics listed in Table 3, year one creatinine values were on average 0.013±0.006 mg/dL (mean ± SE) higher in the calcium treatment group than the control group (P = 0.03).”
Quoted verbatim from Calcium supplementation increases blood creatinine concentration in a randomized controlled trial.. - Study
- RCT
- Dose
- 1200 mg/day elemental calcium as carbonate (600 mg twice daily)
- Population
- Adults aged 45-75 with a recent colorectal adenoma; two calcium arms (calcium alone or with vitamin D3) pooled against two control arms (placebo or vitamin D3 alone); year-one measurement, adjusted for baseline creatinine and other determinants
Effect 0.013 mean difference
Calcium supplementation increases blood creatinine concentration in a randomized controlled trial.2014PMID:2532982110.1371/journal.pone.0108094Permalink