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Papers/PMID:23440843

Selenium supplementation for the primary prevention of cardiovascular disease.

The Cochrane database of systematic reviews2013The record

2 findings · 1 compound · 2 endpoints · 2 null

What it reported

How to read these marks

Every finding here is a null result.

What did not

2 findings

  • selenium atom — no detected effect on incidence of cardiovascular disease (composite)

    Evidence strength: very limited.FindingNull resultreplicated ×1
    “There were no statistically significant effects of selenium supplementation on all cause mortality (RR 0.97, 95% CI 0.88 to 1.08), CVD mortality (RR 0.97, 95% CI 0.79 to 1.2), non-fatal CVD events (RR 0.96, 95% CI 0.89 to 1.04) or all CVD events (fatal and non-fatal) (RR 1.03, 95% CI 0.95 to 1.11).”
    Quoted verbatim from Selenium supplementation for the primary prevention of cardiovascular disease..
    Study
    meta-analysis
    Population
    adults from the general population and adults at high risk of CVD; randomised trials of selenium-only supplementation of at least three months against placebo or no intervention; fatal and non-fatal CVD events combined

    Effect 1.03 risk ratio, 95% CI 0.95 to 1.11

    Selenium supplementation for the primary prevention of cardiovascular disease.2013PMID:2344084310.1002/14651858.CD009671.pub2Permalink

  • selenium atom — no detected effect on all-cause mortality

    Evidence strength: very limited.FindingNull resultreplicated ×3
    “There were no statistically significant effects of selenium supplementation on all cause mortality (RR 0.97, 95% CI 0.88 to 1.08), CVD mortality (RR 0.97, 95% CI 0.79 to 1.2), non-fatal CVD events (RR 0.96, 95% CI 0.89 to 1.04) or all CVD events (fatal and non-fatal) (RR 1.03, 95% CI 0.95 to 1.11).”
    Quoted verbatim from Selenium supplementation for the primary prevention of cardiovascular disease..
    Study
    meta-analysis
    Population
    adults from the general population and adults at high risk of CVD; randomised trials of selenium-only supplementation of at least three months against placebo or no intervention

    Effect 0.97 risk ratio, 95% CI 0.88 to 1.08

    Selenium supplementation for the primary prevention of cardiovascular disease.2013PMID:2344084310.1002/14651858.CD009671.pub2Permalink