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Papers/PMID:21735411

Vitamin D supplementation for prevention of mortality in adults.

The Cochrane database of systematic reviews2011The record

1 finding · 1 compound · 1 endpoint

What it reported

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What moved

1 finding

  • calciol — decreases all-cause mortality

    Evidence strength: very limited.Finding
    “When the different forms of vitamin D were assessed separately, only vitamin D(3) decreased mortality significantly (RR 0.94, 95% CI 0.91 to 0.98, I(2) = 0%; 74,789 participants, 32 trials) whereas vitamin D(2), alfacalcidol, or calcitriol did not.”
    Quoted verbatim from Vitamin D supplementation for prevention of mortality in adults..
    Study
    meta-analysis
    Participants
    74,789
    Dose
    vitamin D3 at any dose, duration and route; median duration of vitamin D administration two years across all trials
    Population
    Adults in 32 randomised trials of vitamin D3 versus placebo or no intervention, mostly elderly women older than 70 years; some trials gave vitamin D3 together with calcium

    Effect 0.94 risk ratio, 95% CI 0.91 to 0.98

    Vitamin D supplementation for prevention of mortality in adults.2011PMID:2173541110.1002/14651858.CD007470.pub2Permalink