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Papers/PMID:20687064

Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.

The Cochrane database of systematic reviews2010The record

2 findings · 1 compound · 2 endpoints

What it reported

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What moved

2 findings

  • Ca(2+) — decreases pre-eclampsia incidence

    Evidence strength: very limited.Findingreplicated ×4
    “There was also a reduction in the average risk of pre-eclampsia associated with calcium supplementation (13 trials, 15,730 women: RR 0.45, 95% CI 0.31 to 0.65).”
    Quoted verbatim from Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems..
    Study
    meta-analysis
    Participants
    15,730
    Dose
    at least 1 g daily
    Population
    Pregnant women in randomised trials of at least 1 g daily calcium versus placebo; most women low risk with a low calcium diet

    Effect 0.45 risk ratio, 95% CI 0.31 to 0.65

    Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.2010PMID:2068706410.1002/14651858.CD001059.pub3Permalink

  • Ca(2+) — decreases preterm birth incidence

    Evidence strength: very limited.Findingreplicated ×3
    “The average risk of preterm birth was reduced in the calcium group overall (11 trials, 15,275 women: RR 0.76, 95% CI 0.60 to 0.97) and amongst women at high risk of developing pre-eclampsia recruited to four small trials (568 women: RR 0.45, 95% CI 0.24 to 0.83).”
    Quoted verbatim from Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems..
    Study
    meta-analysis
    Participants
    15,275
    Dose
    at least 1 g daily
    Population
    Pregnant women in randomised trials of at least 1 g daily calcium versus placebo, overall estimate; most women low risk with a low calcium diet

    Effect 0.76 risk ratio, 95% CI 0.6 to 0.97

    Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems.2010PMID:2068706410.1002/14651858.CD001059.pub3Permalink