Papers/PMID:19606092
Use of transdermal melatonin delivery to improve sleep maintenance during daytime.
Clinical pharmacology and therapeutics2009The record
1 finding · 1 compound · 1 endpoint
What it reported
How to read these marksWhat moved
1 finding
melatonin — decreases core body temperature
Evidence strength: limited.Finding“Melatonin reduced body temperature by ∼0.13°C during the last 4 h of administration.”
Quoted verbatim from Use of transdermal melatonin delivery to improve sleep maintenance during daytime.. - Study
- crossover
- Duration
- 1 day
- Dose
- 2.1 mg melatonin transdermal patch, worn 08:00-18:00 h on day 2
- Population
- Eight healthy volunteers (4 women) in a double-blind crossover with a 2.1 mg transdermal patch worn during an 8-h daytime sleep opportunity; the last 4 h of administration only; rectal sensor
Use of transdermal melatonin delivery to improve sleep maintenance during daytime.2009PMID:1960609210.1038/clpt.2009.109Permalink